Fusariosis manifesting as targetoid purpuric cutaneous lesions in immunocompromised patients

[No abstract available

Thermorheological and textural behaviour of gluten-free gels obtained from chestnut and rice flours

Nowadays, as celiac disease is becoming more common the consumers’ demand for gluten-free products with high nutritional and taste quality is increasing. This work deals with the study of the impact of four novelty gluten-free sources: chestnut flour (Cf), whole rice flour (Rw), Carolino rice flour (Rc) and Agulha rice flour (Ra). Textural, thermorheological and stability performance of gluten-free gels using different experimental techniques were evaluated. Mixed gels were also produced for comparison. Texture parameters were determined from the texture profile analysis using a texturometer. Thermorheological oscillatory measurements were conducted in a stresscontrolled rheometer in order to clarify the kinetics of gel formation and to characterise the structure of the matured gels. The stability of the gels was evaluated using transmittance profiling of the gels under gravitational fields (LUMiSizer®). Texture studies suggested that gels from mixtures of chestnut flour at 30 % and rice flour at 20 % showed the right texture to develop gel-based new desserts. Rheological results showed that the thermal profiles on heating of Cf gels were similar to those obtained for Rw and Ra, whereas Rc gels exhibited a particular pattern. Once the final gelatinisation temperature was achieved, no significant differences on the viscoelastic properties were noticed for all the tested gels. Stability tests showed that gels with Rc should present an industrial advantage over the other assayed formulations, since the stability of these gels is of the order of four times larger

Pediatric urolithiasis: the current surgical management

Children represent about 1% of all patients with urolithiasis, but 100% of these children are considered high risk for recurrent stone formation, and it is crucial for them to receive a therapy that will render them stone free. In addition, a metabolic workup is necessary to ensure a tailored metaphylaxis to prevent or delay recurrence. The appropriate therapy depends on localization, size, and composition of the calculus, as well as on the anatomy of the urinary tract. In specialized centers, the whole range of extracorporeal shock-wave lithotripsy (ESWL), ureterorenoscopy (URS), and percutaneous nephrolithotomy (PCNL) are available for children, with the same efficiency and safety as in adults

The human keratins: biology and pathology

The keratins are the typical intermediate filament proteins of epithelia, showing an outstanding degree of molecular diversity. Heteropolymeric filaments are formed by pairing of type I and type II molecules. In humans 54 functional keratin genes exist. They are expressed in highly specific patterns related to the epithelial type and stage of cellular differentiation. About half of all keratins—including numerous keratins characterized only recently—are restricted to the various compartments of hair follicles. As part of the epithelial cytoskeleton, keratins are important for the mechanical stability and integrity of epithelial cells and tissues. Moreover, some keratins also have regulatory functions and are involved in intracellular signaling pathways, e.g. protection from stress, wound healing, and apoptosis. Applying the new consensus nomenclature, this article summarizes, for all human keratins, their cell type and tissue distribution and their functional significance in relation to transgenic mouse models and human hereditary keratin diseases. Furthermore, since keratins also exhibit characteristic expression patterns in human tumors, several of them (notably K5, K7, K8/K18, K19, and K20) have great importance in immunohistochemical tumor diagnosis of carcinomas, in particular of unclear metastases and in precise classification and subtyping. Future research might open further fields of clinical application for this remarkable protein family

Quantifying geological structures of the Nigde province in central Anatolia, Turkey using SRTM DEM data

WOS: 000261956200006A digital terrain model and a 3D fly-through model of the Nigde province in central Anatolia, Turkey were generated and quantitatively analyzed employing the shuttle radar topographic mission (SRTM) digital elevation model (DEM). Besides, stream drainage patterns, lineaments and structural-geological features were extracted and analyzed. In the process of analyzing and interpreting the DEM for landforms, criteria such as color and color tones (attributes of heights), topography (shaded DEM and 3D fly-through model) and stream drainage patterns were employed to acquire geo-information about the land, such as hydrologic, geomorphologic, topographic and tectonic structures. In this study, the SRTM DEM data of the study region were experimentally used for both DEM classification and quantitative analysis of the digital terrain model. The results of the DEM classification are: (1) low plain including the plains of Bor and Altunhisar (20.7%); (2) high plain including the Misli (Konakli) plain (28.8%); (3) plateau plain including the Melendiz (Ciftlik) plateau plain (1.0%); (4) mountain including the Nigde massif (33.3%); and (5) high mountain (16.2%). High mountain areas include a caldera complex of Mt Melendiz, Mt Hasan and Mt Pozanti apart from the Ala mountains called Aladaglar and the Bolkar mountains called Bolkarlar in the study region (7,312 km(2)). Analysis of both the stream drainage patterns and the lineaments revealed that the Nigde province has a valley zone called Karasu valley zone (KVZ) or Nigde valley zone (NVZ), where settlements and agricultural plains, particularly the Bor plain in addition to settlements of the Bor town and the central city of Nigde have the most flooding risk when a heavy raining occurs. The study revealed that the NVZ diagonally divides the study region roughly into two equal parts, heading from northeast to southwest. According to the map created in this study, the right side of the NVZ has more mountainous area, where the Aladaglar is a wildlife national park consisting of many species of fauna and flora whereas the left side of the NVZ has more agricultural plain, with exception of a caldera complex of Mt Melendiz and volcanic Mt Hasan. The south of the study region includes the Bolkarlar. In addition, the Ecemis fault zone (EFZ) lying along the Ecemis rivulet, running from north to south at the west side of the Aladaglar, forms the most important and sensitive location in the region in terms of the tectonics

Digital terrain analysis using Landsat-7 ETM+ imagery and SRTM DEM: a case study of Nevsehir province (Cappadocia), Turkey

WOS: 000257034800011A three-dimensional (3D) model of land-use/land-cover (LULC) and a digital terrain model of Nevsehir province (Cappadocia), Turkey, were generated and analysed using a Landsat-7 Enhanced Thematic Mapper Plus (ETM+) multispectral image set and a Shuttle Radar Topographic Mission (SRTM) digital elevation model (DEM). Stream drainage patterns, lineaments and structural-geological features (landforms) were extracted and analysed. In the process of analysing and interpreting the multispectral images of geological features, criteria such as colour and colour tones, topography and stream drainage patterns were used to acquire information about the geological structures of the land, including as geomorphological, topographic and tectonic structures. Landsat-7 ETM+ multispectral imagery and an SRTM DEM of the study region were used experimentally for classification and analysis of a digital terrain model. Using the multispectral image data, the LULC types were classified as: settlement (1.2%); agricultural land (70.1%); forest (scrubland, orchard and grassland) (2.9%); bare ground (25.5%); and water bodies (lakes and rivers) (0.3%) of the study area (5434km(2)). The results of the DEM classification in the study area were: river flood plain (11.3%); plateau (52.3%); high plateau (28.4%); mountain (7.6%); and high mountain (0.3%). Lineament analysis revealed that the central Kizilirmak River divides the region into two nearly equal parts: the Kirsehir Plateau in the north and the Nevsehir Plateau in the south. In terms of the danger of catastrophe, the settlements of Kozakli, Hacibektas and Acigol were found to be at less risk of earthquake and/or flooding than those of Avanos, Gulsehir, Urgup, Nevsehir, Gumuskent and Derinkuyu, which are located on river flood plains and/or the main stream drainage channels, particularly stream beds, where the lineaments are deep valleys or fracture or fault-line indicators

Localized blastomycosis-like pyoderma with good response to cotrimoxazol and cryotherapy

Blastomycosis-like pyoderma is an unusual, exaggerated, vegetative-tissue reaction to a prolonged primary or secondary bacterial infection. It is a rare disease, usually seen in immunocompromized patients. We report a case of localized blastomycosis-like pyoderma responding poorly to classic treatments, but that gave a dramatic response to a combination treatment of cotrimoxazol and cryotherapy